I was looking up some stuff regarding the history of the discovery of the structure of DNA, and I found that one of the people who's work heavily contributed to making this possible is Erwin Chargaff , who was born in Chernovtsy! Cool, huh?
Chargaff was born in Czernowitz on August 12, 1905, Bukowina, Austria, which is now Chernovtsy , Ukraine.
Erwin Chargaff (Czernowitz, August 11, 1905 ? New York City, USA, June 20, 2002) was an Austrian biochemist who emigrated to the United States during the Nazi era. Through careful experimentation, Chargaff discovered two rules that helped lead to the discovery of the double helix structure of DNA.
More about his scientific work:
Erwin Chargaff proposed two main rules in his lifetime which were appropriately named Chargaff's rules. The first and best known achievement was to show that in natural DNA the number of guanine units equals the number of cytosine units and the number of adenine units equals the number of thymine units. In human DNA, for example, the four bases are present in these percentages: A=30.9% and T=29.4%; G=19.9% and C=19.8%. This strongly hinted towards the base pair makeup of the DNA, although Chargaff was not able to make this connection himself.
For this research, Chargaff is credited with disproving the tetranucleotide hypothesis (Phoebus Levene's widely accepted hypothesis that DNA was composed of a large number of repeats of GACT). Most workers had previously assumed that deviations from equimolar base ratios (G = A = C = T) were due to experimental error, but Chargaff
documented that the variation was real, with [C + G] typically being slightly less abundant. He was able to do this with the newly developed paper chromatography and ultraviolet spectrophotometer. Chargaff met
Francis Crick and James D. Watson at Cambridge in 1952, and, despite not getting on well with them personally, explained his findings to them.
Chargaff's research would later help Watson and Crick to deduce the double helical structure of DNA.
Thought you might find this interesting.